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-Titulo Original : Gene Machine The Race To Decipher The Secrets Of The Ribosome
-Fabricante :
Basic Books
-Descripcion Original:
A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biologys most important molecule Ramakrishnans writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end. -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnans unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the worlds best scientists. In the end, Gene Machine is a frank insiders account of the pursuit of high-stakes science. Review It is [Ramakrishnans] full embrace of the role of the antihero that makes Gene Machine so much fun to read and also serves as a reminder to us all of the beating human heart that lies at the center of every advance in science. Wall Street Journal An engaging and witty memoir... This profoundly human story is written with honesty and humility... This lucid and highly readable account will be enjoyed by students in any of the sciences, by those interested in the history of science, or who love reading memoirs. But really, I think that anyone who is captivated by an absorbing story well told will find much to appreciate in this fascinating book. Forbes [An] absorbing account. Scientific American In Gene Machine, [Ramakrishnan] thoughtfully embeds his trajectory in a wider meditation on how scientists make the decisions that lead to success or failure--and on how they struggle to solve complex problems... anyone who wants to know how modern science really works should read it. Its all here: the ambition, jealousy and factionalism--as well as the heroic late nights, crippling anxiety and disastrous mistakes--that underlie the apparently serene and objective surface represented by the published record. Nature Choice award for outstanding academic titlesAn enchanting and invigorating work, Gene Machine casts a many-angled light on the world of science, the nature of discovery, and on one of the deepest mysteries of twentieth-century biology. Ramakrishnan, one of the key players in deciphering the molecular basis of protein translation, gives us both a rollicking scientific story and a profoundly human tale. In the tradition of The Double Helix, Gene Machine does not hesitate to highlight the process by which science advances: moving through fits and starts, often underscored by deep rivalries and contests, occasionally pitching towards error and misconception, but ultimately advancing towards profound and powerful truths. An outsider to the world of ribosome biology--an Indian immigrant, a physicist by training--Ramakrishnan retains his outsiders vision throughout the text, reminding us about the corrosive nature of scientific prizes, and the intensity of competition that drives researchers (both ideas, I suspect, will have a munificent effect on our current scientific culture). Ramakrishnans writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end. Siddhartha MukherjeeIf someone had told me that one of the most witty and enthralling books Id read this year would be on the quest to understand ribosomes, I believe I would have laughed in his face, but I would have been quite wrong. Gene Machine is beyond superb. Bill BrysonThe ribosome, a structure of astonishing complexity, lies at the crossroads of
-Fabricante :
Basic Books
-Descripcion Original:
A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biologys most important molecule Ramakrishnans writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end. -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnans unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the worlds best scientists. In the end, Gene Machine is a frank insiders account of the pursuit of high-stakes science. Review It is [Ramakrishnans] full embrace of the role of the antihero that makes Gene Machine so much fun to read and also serves as a reminder to us all of the beating human heart that lies at the center of every advance in science. Wall Street Journal An engaging and witty memoir... This profoundly human story is written with honesty and humility... This lucid and highly readable account will be enjoyed by students in any of the sciences, by those interested in the history of science, or who love reading memoirs. But really, I think that anyone who is captivated by an absorbing story well told will find much to appreciate in this fascinating book. Forbes [An] absorbing account. Scientific American In Gene Machine, [Ramakrishnan] thoughtfully embeds his trajectory in a wider meditation on how scientists make the decisions that lead to success or failure--and on how they struggle to solve complex problems... anyone who wants to know how modern science really works should read it. Its all here: the ambition, jealousy and factionalism--as well as the heroic late nights, crippling anxiety and disastrous mistakes--that underlie the apparently serene and objective surface represented by the published record. Nature Choice award for outstanding academic titlesAn enchanting and invigorating work, Gene Machine casts a many-angled light on the world of science, the nature of discovery, and on one of the deepest mysteries of twentieth-century biology. Ramakrishnan, one of the key players in deciphering the molecular basis of protein translation, gives us both a rollicking scientific story and a profoundly human tale. In the tradition of The Double Helix, Gene Machine does not hesitate to highlight the process by which science advances: moving through fits and starts, often underscored by deep rivalries and contests, occasionally pitching towards error and misconception, but ultimately advancing towards profound and powerful truths. An outsider to the world of ribosome biology--an Indian immigrant, a physicist by training--Ramakrishnan retains his outsiders vision throughout the text, reminding us about the corrosive nature of scientific prizes, and the intensity of competition that drives researchers (both ideas, I suspect, will have a munificent effect on our current scientific culture). Ramakrishnans writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end. Siddhartha MukherjeeIf someone had told me that one of the most witty and enthralling books Id read this year would be on the quest to understand ribosomes, I believe I would have laughed in his face, but I would have been quite wrong. Gene Machine is beyond superb. Bill BrysonThe ribosome, a structure of astonishing complexity, lies at the crossroads of
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